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The Journal of AOAC INTERNATIONAL is dedicated to publishing basic and applied research in the analytical sciences related to foods, drugs, agriculture, and the environment. Emphasis is on research and development of precise, accurate, sensitive methods of analysis in the following areas:

Scope of Journal Sections

Animal and Plant Nutrition, Health, and Safety, Section Editor: Nancy Thiex
The scope of this section includes sampling studies of agricultural commodities, ingredients, and products, and sample preparation of agricultural laboratory samples. Such studies should report error associated with specific protocols for specific materials and include a scholarly description of the study design for a specific analyte, analyte concentration, acceptable error, incorporation of sampling quality control.

Single-laboratory validation reports are published for new analytical methods for matrices such as grain, feed ingredients, forage, mixed feeds, fertilizers, blended fertilizers, soil amendments, pesticide formulations, animal tissues, soils, etc. Examples of analytes are nutrients, minerals, additives (e.g, drugs, antibiotics, vitamins) and contaminants or non-nutritive target analytes that are naturally occurring or adulterants. Generally, these methods are of importance for commerce (labeling or pricing) or for the purposes of animal health and food/feed safety.

The Journal also publishes studies comparing analytical methods and bias and new analytical techniques as applied to matrices and analytes described above. Modifications of analytical methods to improve method performance, or expansion of scope of currently validated methods. Review articles for any of the above topics. Manuscripts that are of significance in the regulation of commerce of materials, other than analytical method validation. These may discuss analytical tolerances, analytical error or data acceptance criteria, risk assessment, etc.

Dietary Supplements, and Food Chemical Contaminants, Section Editor: Paula Brown
The Journal publishes basic and applied research in the analytical sciences related to food chemical contaminants (seafood toxins, mycotoxins) and dietary supplements, with emphasis on the development of new analytical methods, particularly those used in the regulation of foods, the application of such methods to new matrices, the validation of such methods, and occasionally, the use of such methods in surveys and in check sample programs (proficiency testing programs). Priority is given to analytical methods arising from the activities of AOAC stakeholder panels and the working groups associated with such panels.

Drug Formulations and Clinical Methods, Section Editors: Samir Wahab and Joe O. Boison
This section focuses on analytical methods used to identify and analyze pharmaceutical ingredients and products. Concerns that are secondary include the analysis of chemicals and products related to pharmaceutical excipients and dietary supplements. The scope spotlights modern analytical methodologies and technologies and, at the same time, provides opportunities to include some basic methodologies for assisting less developed countries in screening and guarding against any substandard and counterfeit drugs in their areas and marketplaces. Biological work and dosage form performance testing and studies are outside the scope of this section.

Food Biological Contaminants, and Microbiological Methods, Section Editor: Anthony D. Hitchins
Publications of the Journal include single- and multilaboratory collaborative studies of qualitative and quantitative methods for the detection and identification of the pathogenic, indicator and beneficial microbes, and the natural microflora found in foods, feeds, cosmetics, drugs and their production environments. Manuscripts about immunological, nucleic acid, whole genome, and biochemical detection and identification, are considered, including microbe based bioassays. Also considered are reports of studies on detection of airborne biothreat microbes. The analytes of interest include bacteria, fungi and molds, protozoa, algae and viruses. In addition, manuscripts about methods for assessing the efficacy of disinfectants and preservatives and the microbial properties of biofilms are appropriate. Clinical microbiology methods submissions, especially reviews, can be considered only if they indicate their relevance and/or potential applicability to the pathogenic microbes that may occur in the Journal’s listed matrixes of interest.

Food Composition and Additives, and Infant Formula and Adult Nutritionals, Section Editor: Sarwar Gilani
This section publishes basic and applied original research in the analytical sciences, including development of precise, accurate, and sensitive methods, related to major (macronutrients), and minor components (micronutrients, bioactive constituents, additives, and contaminants) of food; chemistry and biochemistry; physiological; nutritional and health; sensory and flavor aspects; and effects of processing and other technologies on compositional quality and safety of foods. This section encourages publication of reviews and invited special sections dealing with methodology, nutritional, health and safety, and regulatory aspects of major and minor components of food.

Residues and Trace Elements, Section Editor: Alexander J. Krynitsky
The section on Residues and Trace Elements seeks unpublished original methods; further studies of previously published methods; and background work leading up to a method. The emphasis is on research, development, and validation of accurate, sensitive methods for the analysis of foods, dietary supplements, cosmetic products, and the environment with regard to trace elements and organic chemical residues. The organic chemical residues include classes of compounds such as pesticides; polynuclear aromatic hydrocarbons (PAHs); persistent organic pollutants (POPs, i.e., halogenated hydrocarbons) and other industrial chemicals that could potentially affect the public health and the environment.

Statistical Analysis and Chemometrics, Section Editor: George W. Latimer, Jr.
The Journal invites papers which provide statistical information about analytical method performance, e.g., both method reproducibility and repeatability; comparison of actual method statistics versus those calculated for a method (the HorRat); conformance to analytical models of response to data, e.g., calibration, comparison of methods, or how a given statistical approach can be used to mine more information from given sets of data.

Chemometric papers should extend the possibilities of analytical techniques or provide re-interpretation of previously published data. Examples are (1) prediction of elution order in a given chromatographic system based on structure, (2) qualitative and quantitative estimation of particular ingredients in mixtures using appropriate preprocessing and multivariate calibration to resolve overlapped chromatographic or spectrographic peaks, and (3) discussion on when noise and background removal techniques can be used to increase sensitivity.

Veterinary Drug Residues, Section Editor: Joe O. Boison
The section on veterinary drug residues will consider high-quality analytical methods developed and validated to monitor and safeguard the use of veterinary drugs in raw or processed foods (fruits and vegetables, dairy, honey, etc.) and agriculture and aquaculture matrixes. Manuscripts dealing with existing and/or previously published analytical methods should offer a significant, original application of the method or a major improvement other than just state-of-the-art. Such manuscripts describing the application of an existing method, even when modified, should be driven by the application (e.g., drug residue depletion studies, pharmacokinetic studies in edible animal tissues and offal, regulatory monitoring studies, etc.) intended to protect the health of the consumer of the edible food product and to facilitate both domestic and international trade.

The section will consider for publication, original research that is expected to have a definable impact on the advancement of science and technology, incorporating a significant component of innovative chemistry and/or molecular biology; reviews that comprehensively summarize information in a field in which the literature is scattered and/or treat published data or other information so as to provide a new approach or stimulate further research; and, presentations at symposia or selected topics comprising a series of manuscripts reporting or synthesizing original research that are presented in a symposium held at AOAC annual meetings or otherwise clustered around a single topic on drug residues.

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